منابع مشابه
Cardiomyopathy of Chagas' Disease
C hagas' disease, or American trypanosomiasis, is caused by the hemoflagellate Trypanosoma cruzi and is the leading cause of cardiac disease in South and Central America. The insect vector occupied the attention of Charles Darwin during a voyage to Argentina in 1888, when he described in detail its peculiar nocturnal blood-sucking habits. Indeed, Darwin's own subsequent clinical symptoms have b...
متن کاملCardiomyopathy protection in Chagas Disease
There is some published evidence suggesting micro vascular endothelial dysfunction and dysautonomia involvement in Chagas disease in association with cardiomyocyte changes favoring disease progression. The combined treatment between angiotensin converting enzyme (ACE) inhibitor drugs; Simvastatin, muscarinic antibody immunoadsorbent together with fungicidal drugs would open therapeutic possibil...
متن کاملChagas Disease Cardiomyopathy: Immunopathology and Genetics
Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and affects ca. 10 million people worldwide. About 30% of Chagas disease patients develop chronic Chagas disease cardiomyopathy (CCC), a particularly lethal inflammatory cardiomyopathy that occurs decades after the initial infection, while most patients remain asymptomatic. Mortality rate is higher than that ...
متن کاملCognitive dysfunction in chronic Chagas disease cardiomyopathy
Chagas disease (CD) remains a major cause of stroke in developing countries, but cognitive repercussion of CD has not been well studied. Objective To compare the frequency and pattern of cognitive dysfunction in patients with CD cardiomyopathy (CDC) and other cardiomyopathies (OC). Methods We studied 37 patients with CDC and 42 patients with OC with similar age, educational level and cardia...
متن کاملChagas' Cardiomyopathy
Background The fundamental determinant of the natural history of Chagas' disease is cardiac involvement. Methods and Results We studied 104 male patients with congestive heart failure due to Chagas' disease to estimate the survival distribution function and to evaluate age, functional class (FC), maximal oxygen consumption (Vo2max ), and ejection fraction (EF) as predictors of survival. Statist...
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ژورنال
عنوان ژورنال: International Journal of Cardiovascular Sciences
سال: 2018
ISSN: 2359-4802
DOI: 10.5935/2359-4802.20180011